New cartoons, Oct. 21

Today’s topics: B cells (in honour of Klaus Rajewsky’s upcoming birthday) and “pitfalls” when strolling along the cell membrane…









As usual, feel free to use and repost, just cite “copyright 2016 by Russ Hodge” and link to



It’s not over until the fat lady sings

An algorithm to end your paper with a bang, not a whimper

You’ve just finished the Best Paper Ever Written, but something’s missing: that perfect last sentence that will make your readers jump from their seats and shout, “Encore! Encore!” They shouldn’t leave before the soprano hits her highest note. What’s the secret? Here’s an algorithm – distilled from thousands of high-impact papers – that practically guarantees success.

Method:  Two readers, working independently, read the same paper and wrote down the last sentence. In a second step they met to drink very strong coffee and compare data. Surprisingly, the results were sometimes in disagreement. Whoever made the mistake had to buy the coffee. Subsequently, the same steps were repeated on 20,000 more papers, over a period of time that seemed infinite but was likely somewhat shorter. At regular intervals coffee was withheld and whiskey was administered, as a means of ameliorating neurological symptoms and reducing the likelihood of  cardiac incidents. When 20,000 sentences had been collected, a systematic comparison was undertaken. Initially this produced no results, due to the inability of the researchers to detect patterns or even stand up most of the time. After six months in a rehabilitation center, their cognitive abilities had returned somewhat and the data was submitted to a second round of analysis. This yielded a model and a powerful algorithm that generates the final sentence for any paper, in a high-throughput way, with very minimal input from the author.


Results:  Most high-impact papers end in this sentence (n = 13,521; p < 0.05):

This suggests that our work will surely open new avenues in the diagnosis of individuals suffering from cancer.

Astoundingly, this is true even for papers that don’t mention cancer at all and fail to provide evidence of any connection to cancer. Of course it’s almost impossible to rule out a connection; with a little creativity, anything can be connected to anything, including Kevin Bacon. We all know that the best way to demonstrate that something is connected to cancer is to claim, in print, that it is not: within days somebody will find some sort of link.

In nearly all the other papers, authors changed a few words to include their own content but kept the structure of the model sentence. This provided a template for the algorithm:

This  1   that   our  2  will    3      4    new  5   in the    6   of  7   suffering from   8 .

The algorithm can be used by anyone capable of following simple instructions: From each column below, choose the word that best fits your research, then put it in the corresponding slot in the following model sentence:


1 2 3 4 5 6 7 8
suggests work likely open avenues diagnosis individuals cancer
implies discovery surely lead to approaches treatment patients Alzheimer’s disease
proves findings definitely trigger insights quality of life domestic animals old age
indicates results obviously stimulate fields sanity children excessive verbosity
demonstrates project clearly boost disciplines health chickens domestic


urges secret videos inevitably excite ion channels sexual gratification teenagers hormone


concludes conclusions conclusively bring to a conclusion dead ends mortality senior citizens terminal old age
proclaims proclamations permanenty provoke pathways proselytization popes priapism
proclaims pronouncements omnisciently ignite mule paths removal of nutcases promiscuity
confirms excretions necessarily inflame intestinal canals presence of physicians lack of sleep
fantasizes random musings perfectly hurl gastrointestinal tracts longevity of political prisoners STDs
states considerations considerably push Autobahns socialization of condemned prisoners prion diseases
foresees algorithm astutely impassion windows education of students hallucinations
hints ideas definitively grope with hiking paths conceptual development of torreadors a case of the giggles
threatens witticisms assuredly throw open corridors disposal of stray pets poor hygeine
instructs teachings succinctly emit fish hatcheries recovery of vicious animals messiness
promulgates lessons exhaustively exude routes death of viruses body odor
presupposes commandments heavily reduce considerations occupational therapy of queens/ other titles of royalty poor self-esteem
attests theories limitlessly disgust red carpets domestic situation of insects split personality disorders
promotes hypotheses infinitely digest trap doors visa status of rocks the attention of a two-year-old
dispells treatises obnoxiously fling aside drive-throughs marital status of irrationally happy people public intoxication
concurs dissertation quirkily discard escalators enjoyment of saftey inspectors idiosyncracies
occludes paper dramatically continue litter boxes eyes of television


writer’s block
announces grant application significantly enhance start-ups pockets of alien life forms library fines
broadcasts YouTube video meaningfully display cat videos retirement parties of professors projectile


tweets workshop stultifyingly expose body parts electrical sockets of blind dates fatal hiccups
predicts examinations clearly sharpen views lenses of myopic people new bifocals

In rare cases, the most fitting words for your project will all be found in one row:

This  concludes  that   our  conclusions  will  conclusively  bring to a conclusion  new dead ends  in the  mortality  of  senior citizens  suffering from  terminal old age.

But in most cases you will need to mix items from different rows, producing sentences like this:

This proclaims that our project will omnisciently inflame gravel roads in the recovery of royalty suffering from poor self-esteem.


This hints that our witticisms will succinctly enhance new escalators in the recovery of chickens with poor hygeine.


The power of the algorithm lies in the number of possible combinations it can produce: namely, 258. Somewhere in this galaxy of sentences must be one that adequately describes your project. If not, you should probably change topics.


The sentence produced by this algorithm should be put at the end of the “Discussion” section. “Discussion” was coined by combining the words “Discus” and “concussion”, reflecting the fact that a good paper should have an impact. A good discussion compresses the paper’s data into a heavy object, if possible with a good aerodynamic shape, and hurls it high into the atmosphere. A high-impact paper will return with such force that anyone struck by it will require medical attention. To avoid being struck yourself, which is embarrassing, never throw your discussion straight up. This suggests that our work will surely open new avenues in the diagnosis of individuals suffering from cancer.

All material on this website copyright 2016 by Russ Hodge

The Devil’s dictionary, Oct. 9 update

See the complete Devil’s Dictionary of Scientific Words and Phrases here.



offal  something inside an animal that is removed so that it can be eaten by another animal, thus returning to the inside where it belongs. An example is the Scotish dish haggis, made by thrusting a hand into the mouth of a sheep so forcefully that it passes all the way through and emerges from the other end, then grasping the tail and executing a sudden jerk in the headwards direction until the sheep is turned inside out, with its intestines on the exterior. After seasoning, the animal is roasted or baked until it shows no further signs of resistance. The first time an Englishman saw this practice he called it “awful”, to the great pleasure of the Scots, whose esteem for anything (such as the EU) rises in direct proportion to the degree of displeasure it causes the English. The Scots proudly began calling their dish “awful” haggis, but their pronunciation made it sound like “offal” to the English, who readopted it as a term to refer to “any innards that only a barbarian would eat.”

Organs that have been extracted for the purpose of transplantation are not normally considered offal, unless they are eaten by mistake. Vomit is considered offal by cats, but not humans, except in the case of projectile vomiting, which in the most severe cases includes bits of organs.

An example of the word’s proper use can be found in the sentence: “How awful is a wall of falafal full of offal.”

efflux  something that comes out of a body, usually involuntarily. Removed from its natural environment and placed, for example, on the sidewalk, or on your dinner plate, efflux usually generates a sense of disgust and nausea, because you realize that there is more of the stuff in your body. This usually leads to reflux. From a legal standpoint, efflux has the same status as garbage: once you’ve put it out on the street, it becomes public property. Dogs may come by and roll in it. DNA samples may be taken from it without a warrent. You can no longer patent it. Anyone is free to come by in a pick-up truck, take it away, and display it on their lawn, or sell it on e-bay, or use it as the basis of a start-up company.

influx  to pick up some efflux and insert it into your body, usually via the mouth, which frequently triggers reflux. If the material originally came from your own body, this is not considered cannibalism.

reflux  to eject a disgusting substance from your body for a second time by, for example, vomiting. The first time it came out it was efflux. After studying the contents of, for example, the vomit you decided it contained something your body needed, such as a kidney, and tried to return it to its natural environment (influx). The second rejection is the reflux. By this point most people figure out that the body is rejecting the substance and give up. But the literature reports a few cases of triflux, quintiflux, and a pathological condition called millifluxitis.


All entries in the Devil’s Dictionary are copyrighted 2016, by Russ Hodge, and may be freely used by citing the author and this website.


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